Dr. Stuart MacNeill

Archaeal research in the MacNeill lab is primarily focused on investigating the molecular biology of DNA replication, DNA repair and genome stability using the genetically-tractable haloarchaeal organisms Haloferax volcanii and Haloarcula hispanica. In addition to this, we also study the function of selected carbohydrate-active enzymes (CAZymes) in Haloarcula hispanica, Haloferax volcanii and related haloarchaea. We use a variety of methods to address questions of protein structure and function, including genetics, genome engineering, cell and molecular biology, biochemistry, structural biology and bioinformatics.